From: "Stuart, Ralph" <Ralph.Stuart**At_Symbol_Here**KEENE.EDU>
Subject: [DCHAS-L] PubChem GHS information update
Date: Tue, 21 Nov 2017 20:09:09 +0000
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: 29FF0017-0052-47F6-812E-4CAACB8D1168**At_Symbol_Here**keene.edu


People familiar with the GHS information available in the National Library of Medicine's PubChem database at
https://pubchem.ncbi.nlm.nih.gov
may be interested to know that the format of this information was recently updated to better reflect GHS information from the European Chemicals Agency (ECHA). Specifically, for chemicals which have a number of reporters that provide varying information, PubChem's entry indicates the percentage of the hazard class reports are based upon, along with the number of reports for that hazard class.

Today, this display has been updated for those chemicals for which most reports "no GHS hazard" to better indicate the number of outliers reported. An example can be found at
https://pubchem.ncbi.nlm.nih.gov/compound/26932#section=GHS-Classification
for PHTHALOCYANINE GREEN
The GHS information from ECHA at PubChem is now reported as
===
GHS Hazard Statements
Aggregated GHS information provided by 888 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Reported as not meeting GHS hazard criteria by 865 of 888 companies. For more detailed information, please visit ECHA C&L website

Of the 3 notification(s) provided by 23 of 888 companies with hazard statement code(s):

H312 (78.26%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (13.04%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
===
The intent is to provide a quick method of assessing the overall quality of the information being reported and to help identify designations that may be particularly appropriate for further investigation.

In addition, further safety information about chemical hazards such as peroxide formers was recently added to the Lab Chemical Safety Summary view for specific chemicals. This change was based on a request from a DCHAS user; further suggestions are encouraged. Feel free to send any questions or suggestions to me for sharing with PubChem staff.

Thanks to the staff at PubChem for their ongoing improvement of this resource!

Let me know if you have any questions about this.

- Ralph


Ralph Stuart, CIH, CCHO
Environmental Safety Manager
Keene State College
603 358-2859

ralph.stuart**At_Symbol_Here**keene.edu

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